Table 4.

Regression Analysis for the Impact of Nutritional Status on EORTC-QLQ Domains

Questionnaire	Subscale	Univariate				Multivariate
		b	95% CI		p	b	95% CI		p
QLQ-C30 — functional scales	Overall quality of life	2.21	1.777	2.643	<0.001*	1.365	0.882	1.849	<0.001*
	Physical functioning	2.463	2.098	2.827	<0.001*	1.682	1.301	2.063	<0.001*
	Role functioning	3.114	2.547	3.682	<0.001*	1.744	1.163	2.326	<0.001*
	Emotional functioning	2.131	1.539	2.724	<0.001*	1.473	0.852	2.094	<0.001*
	Cognitive functioning	2.392	1.953	2.831	<0.001*	1.843	1.346	2.34	<0.001*
	Social functioning	2.142	1.47	2.814	<0.001*	0.915	0.23	1.6	0.009 *
QLQ-C30 — symptom scales	Fatigue	−2.894	−3.393	−2.394	<0.001*	−1.982	−2.527	−1.437	<0.001*
	Nausea and vomiting	−2.126	−2.565	−1.688	<0.001*	−1.652	−2.153	−1.151	<0.001*
	Pain	−2.483	−2.967	−1.999	<0.001*	−1.827	−2.356	−1.297	<0.001*
	Dyspnea	−2.221	−2.735	−1.706	<0.001*	−1.477	−2.056	−0.898	<0.001*
	Insomnia	−2.725	−3.359	−2.091	<0.001*	−1.929	−2.631	−1.227	<0.001*
	Appetite loss	−2.957	−3.528	−2.385	<0.001*	−2.47	−3.189	−1.751	<0.001*
	Constipation	−1.626	−2.198	−1.053	<0.001*	−1.263	−1.975	−0.552	0.001 *
	Diarrhea	−0.911	−1.385	−0.436	<0.001*	−0.655	−1.261	−0.048	0.036 *
	Financial difficulties	−2.586	−3.252	−1.92	<0.001*	−1.074	−1.8	−0.348	0.004 *
QLQ-LC13	Shortness of breath	−2.421	−2.862	−1.981	<0.001*	−1.672	−2.184	−1.161	<0.001*
	Coughing	−1.878	−2.372	−1.385	<0.001*	−1.832	−2.423	−1.241	<0.001*
	Hemoptysis	−1.112	−1.585	−0.639	<0.001*	−0.913	−1.363	−0.463	<0.001*
	Sore mouth or tongue	−1.725	−2.149	−1.302	<0.001*	−0.947	−1.459	−0.434	<0.001*
	Difficulty swallowing	−2.204	−2.639	−1.768	<0.001*	−1.679	−2.216	−1.143	<0.001*
	Tingling in hands or feet	−1.506	−1.97	−1.043	<0.001*	−0.86	−1.396	−0.325	0.002 *
	Hair loss	−1.943	−2.545	−1.342	<0.001*	−1.059	−1.71	−0.409	0.002 *
	Chest pain	−2.131	−2.693	−1.569	<0.001*	−1.329	−1.968	−0.69	<0.001*
	Arm or shoulder pain	−1.033	−1.561	−0.506	<0.001*	−0.597	−1.224	0.029	0.063
	Pain in other body parts	−2.416	−2.999	−1.832	<0.001*	−2.13	−2.886	−1.374	<0.001*
	No improvement with pain medication	−1.114	−1.558	−0.67	<0.001*	−1.143	−1.678	−0.609	<0.001*

Notes: *Statistically significant (p<0.05), b – linear regression coefficient, impact of nutritional status on domains and areas of quality of life.