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. 2021 Feb 12;15:557–576. doi: 10.2147/DDDT.S292417

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© 2021 Yin et al.

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(A) Chemical structure of GKA. (B) Solubility of GKA in different excipients.(C) Pseudo-ternary phase diagrams of blank SNEDDS in K_m value of 1:1, 2:1, 3:1, and 4:1.(D) TEM images of GKA-SNEDDS with the four nanoemulsions (F02, F05, F08 and F11), diluted with distilled water at a ratio of 1:500 and mixed at 37 °C. Scare bar, 200 nm.

Abbreviations: Km ratio, the ratio of surfactant to cosurfactant; S_mix, the mixture of surfactant and cosurfactant.