Table 1.

Synergistic Cytotoxicity of the Combination Treatment of PI-103 and SDT in HepG2 Cells

PI-103		SDT		PI-103 + SDT
Dose (μM)	IR (%)	Dose (μM)	IR (%)	IR (%)	CI
0.5	14.3 ± 1.1	0.5	11.2 ± 0.5	31.0 ± 0.2	0.58
1	27.2 ± 1.0	1	20.1 ± 0.6	36.3 ± 0.4	0.87
2	37.1 ± 1.4	2	31.0 ± 0.3	68.1 ± 0.2	0.39
4	45.4 ± 0.7	4	45.9 ± 0.6	84.5 ± 0.5	0.27
6	51.8 ± 1.2	6	59.4 ± 0.6	89.3 ± 0.4	0.26
8	58.1 ± 0.7	8	74.6 ± 0.3	94.2 ± 0.2	0.18

Abbreviations: IR, inhibition rate; CI, combination index.