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. 2021 Feb 12;14:355–365. doi: 10.2147/JIR.S294238

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© 2021 Shimizu et al.

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Histological examination of the organs. (A) HE-stained organs of MIA/P20 and S/P20 at 24 h. (B) HE-stained liver at 24 h in the MIA and saline groups. (C) Frequency of liver necrosis at 24 h in MIA and saline groups. (D) Immunostaining of cleaved caspase-3 in the liver at 24 h in MIA/P20, S/P20, and S/S. *p < 0.05, Mann–Whitney U-test. Data are represented by mean ± SE. Number of dams = 4 in each group; number of pups = 8–9 in each group. P20, poly(I:C) 20 mg/kg; P4, poly(I:C) 4 mg/kg; S, saline.