Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 12;14:355–365. doi: 10.2147/JIR.S294238

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Shimizu et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Response failure of unfolded protein response in the liver by a second attack in offspring. (A) Relative expression level of Bip mRNA at 2 and 24 h. (B) Relative expression level of Atf4 mRNA at 2 and 24 h. (C) Relative expression level of Atf6 mRNA at 2 and 24 h. (D) Relative expression of Xbp-1t mRNA at 2 and 24 h. (E) Relative expression level of Xbp-1s mRNA at 2 and 24 h. (F) Ratio of expression level of Xbp-1s/Xbp1t mRNA at 2 and 24 h. *p < 0.05, Mann–Whitney U-test. Data are represented by mean ± SE. Number of dams = 4 in each group, number of pups = 8–9 in each group. P20, poly(I:C) 20 mg/kg; P4, poly(I:C) 4 mg/kg; S, saline.