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. 2021 Feb 11;14:37–50. doi: 10.2147/TACG.S276596

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© 2021 Asri et al.

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Gluten protein components and the role of its subgroups in GRDs pathogenesis. According to the results of studies α and γ-gliadins and glutenin are considered to be CD pathogenic responses eliciting factors. The α-gliadin fraction is also reported as DH immunological response triggering agent. Allergic reactivity to the α-/β-, γ- and ω- gliadin fractions and LMW-GS was observed in WA patients. Moreover, patients with NCGS revealed high levels of IgG antibodies against α-, γ- and ω-gliadin and glutenin.

Abbreviations: HMW, high molecular weight; LMW, low molecular weight.