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. Author manuscript; available in PMC: 2021 Feb 16.
Published in final edited form as: Lab Invest. 2017 Jan 23;97(4):478–489. doi: 10.1038/labinvest.2016.158

Figure 3.

Figure 3

Immunohistochemical analysis of thyroid follicles at 10 days after partial thyroidectomy. (a) The primitive follicles exhibiting budding expressed Forkhead box protein A2FOXA2 in nuclei, although most follicular cells were negative for Forkhead box protein A2 (FOXA2). (b) The primitive follicles exhibiting budding were weakly positive or negative for paired box gene-8 (PAX8). (c) The primitive follicles exhibiting budding were negative for thyroid transcription factor-1 (TTF-1). (d) The primitive follicles exhibiting budding demonstrated apical membrane leucine-rich repeat-containing G-protein-coupled receptor 4 (LGR4)/GPR48 expression. Scale bar, 30 μm.