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. 2020 Aug 31;53(3):487–495. doi: 10.1249/MSS.0000000000002498

TABLE 2.

The ICCs of epigenetic age Acc measures and PA indices by zygosity, as well as the correlation coefficients between the measures among young adult (n = 570) and older (n = 470) twins individuals.

ICCs and Their 95% CI Correlation Coefficients and Their 95% CIa,b
MZ DZ 1 2 3 4 5
Young adult twins
 1. DNAm age Acc 0.70 0.61 to 0.79 0.49 0.35 to 0.64
 2. DNAm PhenoAge Acc 0.67 0.58 to 0.75 0.18 0.02 to 0.34 0.35 0.28 to 0.43
 3. DNAm GrimAge Acc 0.67 0.57 to 0.76 0.42 0.22 to 0.62 0.08 −0.01 to 0.17 0.34 0.25 to 0.42
 4. Sport index 0.61 0.48 to 0.75 0.32 0.15 to 0.50 0.09 −0.02 to 0.19 −0.09 −0.19 to 0.01 −0.21 −0.30 to −0.12
 5. Leisure index 0.43 0.27 to 0.58 0.34 0.17 to 0.51 0.05 −0.05 to 0.15 0.03 −0.07 to 0.13 −0.12 −0.21 to −0.02 0.28 0.19 to 0.37
 6. Work index 0.51 0.37 to 0.65 0.26 0.07 to 0.46 −0.01 −0.12 to 0.10 0.00 −0.10 to 0.10 0.26 0.16 to 0.35 −0.06 −0.17 to 0.04 −0.01 −0.11 to 0.10
Older twins
 1. DNAm age Acc 0.62 0.51 to 0.73 0.28 0.15 to 0.41
 2. DNAm PhenoAge Acc 0.62 0.52 to 0.72 0.32 0.13 to 0.52 0.34 0.23 to 0.45
 3. DNAm GrimAge Acc 0.64 0.54 to 0.75 0.40 0.19 to 0.62 0.21 0.11 to 0.31 0.40 0.32 to 0.48
 4. Sport index 0.32 0.15 to 0.50 0.21 −0.04 to 0.46 −0.03 −0.13 to 0.07 −0.06 −0.19 to 0.06 −0.20 −0.31 to −0.08
 5. Leisure index 0.27 0.10 to 0.44 0.26 0.03 to 0.48 −0.12 −0.21 to −0.03 0.00 −0.13 to 0.12 −0.21 −0.31 to −0.12 0.45 0.36 to 0.53
 6. Work index 0.33 0.14 to 0.51 0.34 0.12 to 0.55 0.09 −0.02 to 0.20 0.07 −0.04 to 0.17 0.13 0.03 to 0.23 −0.13 −0.23 to −0.03 −0.02 −0.13 to 0.09

aCIs were corrected for nested sampling.

bSignificant correlations at the level 0.05 are presented in bold.