Table 3.
Analyses of Relative Clinicopathological Factors and FCGBP Expression in Patients
Factor | Patients, No. (Primary) | p-Value | Patients, No. (Metastasis) | p-Value | ||
---|---|---|---|---|---|---|
Negative (n=17) | Positive (n=118) | Negative (n=40) | Positive (n=95) | |||
Age, median (range) (years) | 60 (32–72) | 59 (21–78) | 0.745 | 60.5 (21–74) | 58 (29–78) | 0.539 |
Gender | 0.066 | 0.315 | ||||
Men | 7 | 76 | 22 | 61 | ||
Women | 10 | 42 | 18 | 34 | ||
CEA (range) | 77.049 (1.40–278.90) | 3.880 (0.10–322.20) | <0.001 | 14.239 (1.36–78.90) | 3.890 (0.10–322.20) | 0.008 |
CA19-9 (range) | 111.70 (2.98–665.90) | 8.61 (0.60–827.10) | <0.001 | 19.38 (0.60–418.70) | 7.66 (0.60–827.10) | 0.037 |
Positive nodes | 3 (0–15) | 2 (0–18) | 0.145 | 2 (0–18) | 1 (0–10) | 0.012 |
Clinical tumor (T) classification | 0.492 | 0.352 | ||||
cT2 | 0 | 5 | 3 | 2 | ||
cT3 | 9 | 63 | 21 | 51 | ||
cT4 | 8 | 50 | 16 | 42 | ||
Clinical nodal (N) classification | <0.001 | 0.003 | ||||
cN0 | 5 (29.4%) | 49 (41.5%) | 8 (20%) | 46 (48.4%) | ||
cN1 | 0 (0%) | 46 (39.0%) | 15 (37.5%) | 31 (32.6%) | ||
cN2 | 12 (70.6%) | 23 (19.5%) | 17 (42.5%) | 18 (18.9%) | ||
Perineural invasion | 0.359 | 0.2183 | ||||
Yes | 4 | 41 | 10 | 35 | ||
No | 13 | 77 | 30 | 60 | ||
Venous invasion | 0.923 | 0.511 | ||||
Yes | 8 | 57 | 21 | 44 | ||
No | 9 | 61 | 19 | 51 | ||
Lymphatic invasion | 0.417 | 0.643 | ||||
Yes | 6 | 54 | 19 | 41 | ||
No | 11 | 64 | 21 | 54 |