. 2021 Feb 12;14:59–70. doi: 10.2147/CEG.S290859

Table 2.

Effect of P. dodecandra Root Extract on the Synthetic and Detoxifying Functions of Liver of Mice

Group	Albumin (mg/dL)	Total Protein (g/dL)	Bilirubin (mg/dL)
2%TW80	3.21 ± 0.35	5.62 ± 0.38	1.02 ± 0.42
CCl₄	1.49 ± 0.20^a##	3.78 ± 0.43^a##	3.11 ± 0.51^a###
Silymarin + CCl₄	3.14 ± 0.31^b###	5.40 ± 0.52^b##	1.07 ± 0.44^b###
PDRE100 + CCl₄	1.88 ± 0.19 ^{a###,c###,d#,e##}	4.01 ± 0.61 ^{a##,c##,d##,e##}	2.57 ± 0.25^{a###,c###,d###,e###}
PDRE200 + CCl₄	2.73 ± 0.32^b#	5.18 ± 0.17^b##	1.14 ± 0.39^b###
PDRE400 + CCl₄	3.08 ± 0.15^b###	5.35 ± 0.35^b##	1.10 ± 0.13^b###

Notes: Each value represents mean ± S.E.M; n=6; ^aAgainst 2%TW80; ^bAgainst CCl₄; ^cAgainst standard (silymarin); ^dAgainst PDRE200 + CCl₄; ^eAgainst PDRE400 + CCl₄; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001.

Abbreviations: PDRE100, Phytolacca dodecandra root extract 100 mg/kg; PDRE200, Phytolacca dodecandra root extract 200 mg/kg; PDRE400, Phytolacca dodecandra root extract 400 mg/kg; Silymarin, silymarin 100 mg/kg; CCl₄, carbon tetrachloride 2 mL/kg; 2%TW80, 2% Tween 80 in water.