Table 4.
Effect of 80% Methanol Extract of P. dodecandra Root on Lipid Profile of Mice
| Group | TC (mg/dL) | TG (mg/dL) | HDL (mg/dL) | LDL (mg/dL) |
|---|---|---|---|---|
| 2%TW80 | 95.42 ± 3.18 | 62.39 ± 2.41 | 33.71 ± 1.48 | 42.90 ± 3.04 |
| CCl4 | 52.61 ± 6.42a### | 31.47 ± 5.36 a### | 29.62 ± 2.06 | 26.46 ± 5.13 a### |
| Silymarin + CCl4 | 93.83 ± 3.81b### | 58.26 ± 2.98 b### | 32.54 ± 1.66 | 40.28 ± 2.62 b### |
| PDRE100 + CCl4 | 58.94 ± 6.46a###,c###,d##,e### | 37.80 ± 5.29 a###,c###,d##,e### | 30.19 ± 1.80 | 28.72 ± 3.76 a##,c###,d##,e### |
| PDRE200 + CCl4 | 84.27 ± 2.87 b### | 54.54 ± 4.60 b### | 32.08 ± 2.24 | 36.39 ± 2.11 b### |
| PDRE400 + CCl4 | 91.63 ± 4.22 b### | 57.65 ± 3.21 b### | 32.36 ± 1.98 | 39.85 ± 2.19 b### |
Notes: Each value represents mean ± S.E.M; n=6; aAgainst 2%TW80; bAgainst CCl4; cAgainst standard (silymarin); dAgainst PDRE200 + CCl4; eAgainst PDRE400 + CCl4; ##p < 0.01, ###p < 0.001.
Abbreviations: PDRE100, Phytolacca dodecandra root extract 100 mg/kg; PDRE200, Phytolacca dodecandra root extract 200 mg/kg; PDRE400, Phytolacca dodecandra root extract 400 mg/kg; Silymarin, silymarin 100 mg/kg; CCl4, carbon tetrachloride 2 mL/kg; 2%TW80, 2% Tween 80 in water.