Table 1.

Characteristics of studies in this meta-analysis.

No.	First author	Yr	Country	Design	Composition of control	Detection method	Reference	Reference miRNA	Specimen	Case (male/female)	Age of case	Control (male/female)	Age of control	Selected miRNAs	Expression	Sensitivity	Specificity
1	Sun J	2015	China	Prospective	JSLE	qRT-PCR	AHA	Cel-miR-39	Plasma	26 (N/R)	2.2	20 (N/R)	10.7	miR-1825	Up-regulated	1	1
2	Sheng WW	2016	China	Prospective	HC	qRT-PCR	AHA	U6	Plasma	45 (27/18)	0.3–7	30 (18/12)	0.3–7	miR-145	Up-regulated	0.6444	0.9
														miR-143	Up-regulated	0.6444	0.8667
3	Jia LH	2016	China	Prospective	HC	qRT-PCR	AHA	Cel-miR-39	Plasma	33 (25/8)	2.1	15 (11/4)	1.7	miR-21	Up-regulated	0.846	0.714
4	Rong X	2017	China	Prospective	HC	RT-PCR	JCS	Cel-miR-39	Serum	45 (34/11)	2.1	30 (21/9)	1.7	miR-92a-3p	Up-regulated	0.733	0.889
					FC							30 (23/7)	1.5	miR-92a-3p	Up-regulated	0.733	0.733
5	Zhang W	2017	China	Prospective	HC	qRT-PCR	AHA	U6	Serum	102 (60/42)	2.2	80 (45/35)	2.3	miR-200c	Up-regulated	0.6	0.8
														miR-371–5p	Up-regulated	0.667	0.866
6	Rong X	2018	China	Prospective	HC	qRT-PCR	AHA	Cel-miR-39	Serum	34 (24/10)	2.7	42 (27/15)	3.6	miR-27b	Up-regulated	0.853	1
					FC							15 (10/5)	4.1	miR-27b	Up-regulated	0.676	0.933

AHA = American Heart Association, FC = febrile control, HC = healthy control, JCS = Japanese Cardiology Society, JSLE = juvenile systemic lupus erythematous, miR = mircoRNA, N/R = not report.