Table 4.
Multivariate Analysis for Predictors of Death.
| Predictors | HR (95% CI) | P a |
|---|---|---|
| Age >70 yr | 3.700 (1.500-6.000) | 0.002 |
| Heart disease | 2.738 (1.480-5.065) | 0.001 |
| Hypertension | 1.308 (0.715-2.392) | 0.383 |
| Chronic kidney disease | 3.710 (1.848-7.447) | < 0.001 |
| CURB-65 score ≥2 | 5.963 (3.069-11.588) | < 0.001 |
| Platelets <140 × 109/L | 0.998 (0.528-1.886) | 0.996 |
| Lymphocytes <1000 cells/μL | 1.065 (0.536-2.115) | 0.180 |
| Hemoglobin <12 g/dL | 1.341 (0.670-2.823) | 0.439 |
| High-risk lymphomab (vs low-risk) | 1.256 (0.670-2.356) | 0.476 |
| DLBCL (vs FL) | 1.623 (0.756-3.483) | 0.213 |
| Active treatmentc | 1.681 (0.382-7.407) | 0.493 |
| Active diseased (vs CR) | 2.770 (1.143-6.712) | 0.024 |
P values marked in bold indicate statistically significant results (P < 0.05).
aCox regression.
bHigh-risk according to prognostic index at diagnosis.
cLymphoma treatment within the 3 previous months.
dPartial response or progression.
CI = confidence interval; CR = complete response; CURB-65 = confusion, urea concentration, respiratory rate, blood pressure, and age >65; DLBCL = diffuse large B cell lymphoma; FL = follicular lymphoma; HR = hazard ratio.