Table 3.
Patient characteristics and change in primary outcomes.
Patient | Age (yr) | Sex | Duration of disease (yr) | Pain locations | Completion | Physical comorbidity | Psychiatric comorbidity | Pharmacotherapy | NRS-pre | NRS-mid | NRS-post | PCS-pre | PCS-mid | PSC-pos |
1 | 41 | F | 0.8 | Both legs | Discontinued after the second session. | Gynecological cancer after chemotherapy | None | Pregabalin, duloxetine | 5.4 | 30 | ||||
2 | 52 | M | 1.5 | Low back, left leg, left hand | Discontinued after the fourth session. | Lumbar disc herniation, lumbar spondylolisthesis, bacterial infection bitten by cat. | None | Pregabalin, escitalopram, trazodone | 8.2 | 30 | ||||
3 | 73 | F | 35.0 | Right femur, both legs | Yes | Temporomandibular disorders, fractured wrist due to fall | None | Clonazepam, mirtazapine | 6.7 | 6.0 | 7.8 | 22 | 28 | 24 |
4 | 37 | M | 3.0 | Neck, low back | Yes | cerebral palsy | None | Pregabalin, acetaminophen | 5.3 | 4.1 | 4.3 | 43 | 34 | 31 |
5 | 56 | M | 1.8 | Both legs | Yes | None | None | Duloxetine, methotrexate, acetaminophen, tramadol, prednisolone, clonazepam, mexiletine | 6.0 | 8.0 | 7.0 | 29 | 14 | 6 |
6 | 30 | F | 16.0 | Right intercostal, left abdomen | Yes | Endometriosis, chocolate cyst | Generalized anxiety disorder | Clonazepam, etizolam | 4.0 | 4.7 | 5.4 | 31 | 35 | 37 |
7 | 50 | F | 3.5 | Left leg | Yes | Osteoarthritis | None | Neurotropin, diazepam, duloxetine, valproic acid, clonazepam | 6.0 | 5.0 | 5.0 | 22 | 15 | 15 |
8 | 40 | F | 5.0 | Left heel | Yes | Complex regional pain syndrome, migraine, systemic lupus erythematosus | Moderate risk of suicide, bulimia nervosa | Pregabalin, acetaminophen, tramadol, celecoxib, methotrexate, prednisolone, lomerizine hydrochloride, zolmitriptan, gabapentin | 5.0 | 8.5 | 9.4 | 47 | 45 | 19 |
9 | 66 | F | 30.0 | Left shoulder, neck, right ankle, low back, head | Yes | Hyperlipidemia, insomnia | Depression, dysthymia, obsessive compulsive disorder, post-traumatic stress disorder | Pregabalin, gabapentin, quetiapine, eperisone | 7.6 | 8.3 | 8.6 | 34 | 36 | 34 |
10 | 72 | M | 47.0 | Low back, upper back, abdomen | Yes | Lumbar disc herniation, spinal canal stenosis, intradural extramedullary tumor surgery, malignant thymoma surgery | none | Acetaminophen, tramadol | 8.0 | 8.9 | 8.1 | 40 | 27 | 17 |
11 | 76 | F | 16.0 | Low back, left knee | Yes | Right knee meniscus injury, glaucoma | None | Pregabalin, acetaminophen | 4.0 | 6.1 | 3.6 | 30 | 19 | 15 |
12 | 37 | M | 2.0 | head | yes | none | None | None | 7.1 | 7.1 | 7.2 | 23 | 19 | 22 |
13 | 57 | F | 20.0 | Low back, both legs,lower abdomen | yes | gallbladder stone | Moderate risk of suicide | Methylphenidate, atomoxetine | 9.0 | 5.0 | 6.0 | 42 | 45 | 34 |
14 | 59 | M | 7.0 | Left arm, left shoulder, left buttocks, low back | Yes | Cervical spondylosis, intervertebral foramen stenosis | None | Pregabalin, eszopiclon, loflazepate, trazodone | 2.6 | 1.8 | 1.7 | 25 | 18 | 15 |
15 | 69 | F | 5.0 | Right heel, both legs, both hands | Yes | Rheumatism, diabetes, hyperlipidemia | None | Pregabalin, acetaminophen, tramadol | 3.0 | 2.6 | 3.5 | 32 | 23 | 14 |
16 | 77 | F | 3.0 | Both soles | Yes | Peripheral neuropathy | None | None | 8.0 | 9.8 | 9.0 | 31 | 15 | 21 |
NRS = Numerical Rating Scale, PCS = Pain Catastrophizing Scale.