Table 4.

Relationship between the SNPs and СAR under multiple models of inheritance.

RS	Model inheritance	Control group	СAR group	OR 95%CI	P	OR 95%CI adj. by age	P value adj by age	OR 95%CI adj. by gender	P value adj by gender	OR 95%CI adj. by age and gender	P value adj by age and gender
rs11775334	Codominant
	G/G	66 (32.4%)	85 (23.8%)	1	.03755	1	.07474	1	.03368	1	.06156
	A/G	106 (52%)	192 (53.8%)	1.41 [0.94–2.1]		1.38 [0.89–2.12]		1.44 [0.96–2.15]		1.41 [0.91–2.18]
	A/A	32 (15.7%)	80 (22.4%)	1.94 [1.15–3.27]		1.89 [1.08–3.31]		1.96 [1.16–3.3]		1.93 [1.1–3.39]
	Dominant
	G/G	66 (32.4%)	85 (23.8%)	1	.02936	1	.05585	1	.02345	1	.04337
	A/G–A/A	138 (67.6%)	272 (76.2%)	1.53 [1.05–2.24]		1.5 [0.99–2.26]		1.56 [1.06–2.28]		1.53 [1.01–2.32]
	Recessive
	G/G–A/G	172 (84.3%)	277 (77.6%)	1	.05201	1	.07894	1	.05635	1	.0755
	A/A	32 (15.7%)	80 (22.4%)	1.55 [0.99–2.44]		1.53 [0.94–2.49]		1.54 [0.98–2.43]		1.54 [0.95–2.51]
	Overdominant
	G/G–A/A	98 (48%)	165 (46.2%)	1	.67768	1	.74641	1	.60177	1	.68618
	A/G	106 (52%)	192 (53.8%)	1.08 [0.76–1.52]		1.06 [0.73–1.54]		1.1 [0.78–1.55]		1.08 [0.74–1.57]
	Log-additive
	0,1,2	204 (36.4%)	357 (63.6%)	1.39 [1.08–1.8]	.01042	1.38 [1.04–1.81]	.02275	1.4 [1.08–1.82]	.00933	1.39 [1.06–1.84]	.01827
rs2407103	Codominant
	A/A	143 (70.1%)	223 (62.5%)	1	.01503	1	.01859	1	.01554	1	.01651
	A/G	59 (28.9%)	117 (32.8%)	1.27 [0.87–1.85]		1.29 [0.86–1.95]		1.29 [0.88–1.88]		1.31 [0.87–1.98]
	G/G	2 (1%)	17 (4.8%)	5.45 [1.24–23.95]		6.01 [1.25–28.85]		5.37 [1.22–23.6]		6.09 [1.27–29.2]
	Dominant
	A/A	143 (70.1%)	223 (62.5%)	1	.06627	1	.07206	1	.06038	1	.06261
	A/G–G/G	61 (29.9%)	134 (37.5%)	1.41 [0.97–2.04]		1.44 [0.97–2.14]		1.42 [0.98–2.06]		1.46 [0.98–2.18]
	Recessive
	A/A–A/G	202 (99%)	340 (95.2%)	1	.00902	1	.01132	1	.0101	1	.01076
	G/G	2 (1%)	17 (4.8%)	5.05 [1.15–22.08]		5.53 [1.16–26.42]		4.95 [1.13–21.69]		5.59 [1.17–26.64]
	Overdominant
	A/A–G/G	145 (71.1%)	240 (67.2%)	1	.34267	1	.33737	1	.31492	1	.31097
	A/G	59 (28.9%)	117 (32.8%)	1.2 [0.82–1.74]		1.22 [0.81–1.83]		1.21 [0.83–1.77]		1.23 [0.82–1.85]
	Log-additive
	0,1,2	204 (36.4%)	357 (63.6%)	1.48 [1.07–2.05]	.01678	1.52 [1.06–2.16]	.01975	1.49 [1.07–2.07]	.01566	1.54 [1.07–2.2]	.01668

CAR = carotid artery remodeling, OR = odds ratio, SNP = single nucleotide polymorphism.