Table 2.
Comparison of the root-mean-square deviation (RMSD), the median performance error (MDPE) and absolute median performance error (MDAPE) for expiratory concentrations between measured data from volatile anesthesia in patients and calculated data from simulations.
| Patient vs. standard Gas Man model | Patient vs. parameter-matched Gas Man model | P value | ||
| RMSD (Desflurane) (% Atm.) | Induction | 1.8 (0.4) | 0.9 (0.5) | .001 |
| Maintenance | 0.07 (0.02) | 0.07 (0.02) | .100 | |
| Elimination | 0.7 (0.6) | 0.2 (0.2) | .014 | |
| RMSD (Sevoflurane) (% Atm.) | Induction | 1.2 (0.9) | 0.4 (0.4) | .029 |
| Maintenance | 0.06 (0.01) | 0.06 (0.01) | .100 | |
| Elimination | 0.7 (0.5) | 0.2 (0.2) | .008 | |
| MDPE (%) | Desflurane | 4.7 (3.6) | 5.0 (4.0) | .859 |
| Sevoflurane | ∗4.7 (3.3–6.8) | 4.2 (0.5) | .694 | |
| MDAPE (%) | Desflurane | 5.8 (2.2) | 6.0 (2.5) | .817 |
| Sevoflurane | ∗9.5 (5.6–10.2) | ∗7.6 (4.2–9.0) | .563 |
IQR = interquartile range, MDAPE = absolute median performance error, MDPE = median performance error, RMSD = root mean square deviation. For data that were not normally distributed (∗), values are given in median (IQR).