Table 3.

Univariate and multivariate proportional hazards (Cox) regression analyses according to OS.

	Univariate Cox analysis		Multivariate Cox analysis
Variables in the equation	P	Hazard ratio (95% CI)	P	Hazard ratio (95.0% CI)
Age
<57	–	–
>57	.360	0.793 (0.483–1.303)
Gender
Male	–	–
Female	.572	0.865 (0.523–1.430)
Smoke status
Never	–	–
Smoker	.946	1.020 (0.572–1.818)
Histology
ADC	–	–
Others	.462	0.745 (0.340–1.633)
TNM stage
III	–	–	–	–
IV	.020	2.326 (1.145–4.724)	0.043	2.096 (1.022–4.299)
PLR
<172.88	–	–
>172.88	.053	1.621 (0.993–2.646)
MLR
<0.23	–	–
>0.23	.055	1.690 (0.989–2.887)
NLR
<2.72	–	–
>2.72	.140	1.469 (0.881–2.448)
SII
<841.03	–	–	–	–
>841.03	.017	1.817 (1.114–2.961)	0.049	1.644 (1.002–2.696)
Drug
Icotinib	.322	–
Erlotinib	.141	0.509 (0.207–1.251)
Gefitinib	.324	0.742 (0.411–1.341)