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. 2021 Feb 10;5(3):e532. doi: 10.1097/HS9.0000000000000532

Figure 4.

Figure 4.

Multivariate analyses for outcomes according to BMI difference between diagnosis and allogeneic HSCT and other prognostic variables. Forest plot showing hazard ratios and odds ratios from logistic regression models for nonrelapse mortality and OS, respectively. Variables considered in the models were those significant at α = 0.10 in univariable analyses. For nonrelapse mortality endpoint, variables considered were BM blast count at diagnosis, disease origin (de novo vs secondary AML), BMI at diagnosis (< 25 kg/m2 vs 25 to < 30 kg/m2 vs ≥ 30 kg/m2), age at HSCT, BMI change (ΔBMI > –2 vs ≤ –2), and donor type (HLA mismatch vs matched unrelated vs matched related). For OS endpoint, variables considered were platelet count at diagnosis, BM blasts at diagnosis, disease origin (de novo vs secondary AML), BMI at diagnosis (< 25 kg/m2 vs 25 to < 30 kg/m2 vs ≥ 30 kg/m2), ELN2017 genetic risk group, remission status at HSCT (no CR/CRi vs second CR/CRi vs first CR/CRi), HCT-CI score (0 vs 1/2 vs 3), BMI at HSCT (< 25 kg/m2 vs 25 to <30 kg/m2 vs ≥ 30 kg/m2), BMI change (ΔBMI > –2 vs ≤ –2), and donor type (HLA mismatch vs matched unrelated vs matched related). AML = acute myeloid leukemia; BM = bone marrow; BMI = body mass index; CI = confidence interval; CR = complete remission; CRi = complete remission with incomplete peripheral recovery; ELN = European LeukemiaNet; HCT-CI = hematopoietic cell transplantation comorbidity index; HLA = human leukocyte antigen; HSCT = hematopoietic stem cell transplantation; OS = overall survival.