Table 2.
Univariate and multivariate Cox regression models of factors associated with development of the combined event in the IgAVN cohort
| Variable | IgAVN cohort |
|
|---|---|---|
| Univariate HR (95% CI); P-value | Multivariate HR (95% CI); P-value | |
| Age | 1.03 (0.99–1.06); 0.21 | 1.02 (0.97–1.07); 0.48 |
| Gender (female vs male) | 0.54 (0.22–1.36); 0.19 | 0.69 (0.26–1.85); 0.46 |
| eGFR at renal biopsy | 0.99 (0.98–1.01); 0.32 | 1.001(0.98–1.02); 0.90 |
| Proteinuria at renal biopsy | 1.05 (0.91–1.21); 0.54 | 1.00 (0.85–1.18); 0.99 |
| MAP at renal biopsy | 1.03 (0.99–1.07); 0.20 | 1.02 (0.97–1.07); 0.45 |
| M0 | Reference | |
| M1 | 1.51 (0.6–3.79); 0.38 | |
| E0 | Reference | |
| E1 | 0.53 (0.21–1.36); 0.19 | |
| S0 | Reference | |
| S1 | 1.32 (0.38–4.64); 0.66 | |
| T0 | Reference | Reference |
| T1/2 | 3.53 (1.36–9.17); 0.01 | 2.86 (0.99–8.28); 0.05 |
| C0 | Reference | |
| C1/2 | 1.00 (0.40–2.50); 0.99 | |
Combined event, survival from a 50% eGFR decline or ESRD.