Table 3.
Cross-sectional analyses: baseline data of eGFR and prevalence of stage 1 kidney function (eGFR ≥ 90 mL/min × 1.73 m2) by sex- and age- controlled quintiles of baseline overnight uNa/Cr ratio (mean or prevalence)
| Variable | Quintile of baseline uNa/Cr ratio |
P for trenda | ||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | ||
| Baseline examinees, n | 913 | 919 | 924 | 922 | 917 | |
| Serum creatinine (µmol/L), mean | ||||||
| Non-adjusted | 81.7 | 80.9 | 79.9 | 79.1 | 77.7 | <0.001 |
| Adjustedb | 81.2 | 80.9 | 79.9 | 79.3 | 78.0 | <0.001 |
| eGFR (mL/min/1.73 m2), mean | ||||||
| Non-adjusted | 84.8 | 85.9 | 86.9 | 87.9 | 89.3 | <0.001 |
| Adjustedb | 85.4 | 85.8 | 87.0 | 87.6 | 88.9 | <0.001 |
|
39.1% (357) | 42.7% (392) | 45.2% (418) | 46.6% (430) | 50.6% (464) | <0.001 |
| 1 (reference) | 1.16 (0.96/1.40) | 1.29 (1.07/1.55) | 1.34 (1.11/1.61) | 1.63 (1.35/1.96) | <0.001 | |
| Stage 1 kidney function, adjusted %b | 40.2 | 42.4 | 45.7 | 46.1 | 49.9 | <0.001 |
| Adjusted ORb | 1 (reference) | 1.15 (0.89/1.48) | 1.47 (1.13/1.90) | 1.48 (1.13/1.92) | 1.98 (1.50/2.59) | <0.001 |
a
By linear or logistic regression analysis.
b
Covariates in the multivariable model: sex and baseline data of age, education, physical activity, obesity, smoking, hypertension, cardiovascular disease, diuretic treatment, treatment with ACE inhibitor, diabetes, protein intake, overnight urine potassium, alcohol intake, milk or yogurt intake, intake of caffeine-containing beverages and intake of total fluids.