Table 2.
Characteristics of HD patients with different serum UA concentrations
| Characteristics | FA-UA (µmol/L) |
P-value | ||
|---|---|---|---|---|
| Low (FA-UA <400 µmol/L) (n = 87) | Intermediate (FA-UA 400–450 μmol/L) (n = 67) | High (FA-UA >450 μmol/L) (n = 71) | ||
| Age (years) | 53.8 ± 14.5* | 49.7 ± 14.6* | 42.4 ± 14.0* | 0.0000 |
| HD vintage (months) | 98.5 ± 73.5 | 105.6 ± 69.1 | 115.3 ± 74.0 | NS |
| Diabetes, n (%) | 23 (26.4) | 9 (13.4) | 6 (8.5) | 0.007 |
| CVD, n (%) | 34 (39.1) | 24 (35.8) | 15 (21.1) | 0.039 |
| BMI (kg/m2) | 23.2 ± 3.4* | 23.9 ± 4.6 | 25.2 ± 4.8* | 0.016 |
| SBP (mmHg) | 137 ± 23 | 140 ± 21 | 132 ± 24 | NS |
| DBP (mmHg) | 80 ± 15 | 84 ± 14 | 80 ± 16 | NS |
| Length of HD (minutes) | 236 ± 10* | 241 ± 12* | 243 ± 11* | 0.001 |
| Hemoglobin (g/L) | 104.0 ± 12.9* | 107.1 ± 12.9 | 110.0 ± 11.6* | 0.012 |
| Ultrafiltration (L) | 2.9 ± 0.7* | 3.1 ± 0.8* | 3.6 ± 0.8* | 0.000 |
| Single-pool Kt/V | 1.25 ± 0.23 | 1.23 ± 0.19 | 1.24 ± 0.19 | NS |
| nPCR (g/kg/day) | 1.08 ± 0.144* | 1.11 ± 0.12 | 1.14 ± 0.12* | 0.008 |
| Creatinine (µmol/L) | 810.6 ± 163.2* | 959.8 ± 156.2* | 1013.2 ± 228.0* | 0.000 |
| Calcium (mmol/L) | 2.27 ± 0.12 | 2.32 ± 0.16 | 2.28 ± 0.15 | NS |
| Phosphorus (mmol/L) | 1.41 ± 0.33* | 1.56 ± 0.35* | 1.53 ± 0.34 | 0.018 |
| Albumin (g/L) | 37.7 ± 3.6* | 39.3 ± 2.5* | 38.7 ± 3.1 | 0.008 |
| HDL cholesterol (mmol/L) | 1.04 ± 0.30* | 1.02 ± 0.21 | 0.93 ± 0.26* | 0.025 |
| LDL cholesterol (mmol/L) | 2.68 ± 0.82 | 2.67 ± 0.83 | 2.60 ± 0.97 | NS |
| iPTH (pg/mL), median (IQR) | 88.3 (51–233) | 138.7 (69–297) | 177 (102–309) | NS |
| BNP (pg/mL), median (IQR) | 935 (548–1894) | 860 (358–1349) | 698 (369–1527) | 0.054 |
| CRP (mg/L), median (IQR) | 10.3 (3.7–23)* | 5.7 (3.8–11.9)* | 8.2 (3.8–17.9) | 0.044 |
| LVMI (g/m2) | 153.1 ± 59.9* | 131.6 ± 41.0* | 131.2 ± 44.5* | 0.029 |
Data are presented as mean ± SD unless stated otherwise.
Low group = 1, intermediate group = 2, high group = 3/age (1 versus 3, P = 0.000; 2 versus 3, P = 0.008), BMI (1 versus 3, P = 0.011), nPCR (1 versus 3, P = 0.005), HDL cholesterol (1 versus 3, P = 0.024), hemoglobin (1 versus 3, P = 0.007), phosphorus (1 versus 2, P = 0.019), albumin (1 versus 2, P = 0.006), CRP (1 versus 2, P = 0.032), ultrafiltration (1 versus 3, P = 0.00; 2 versus 3, P = 0.001), creatinine (1 versus 2, P = 0.000; 1 versus 3, P = 0.000), length of HD (1 versus 2, P = 0.000; 1 versus 3, P = 0.034), LVH (1 versus 2, P = 0.042; 1 versus 3, P = 0.038).
iPTH, intact parathyroid hormone; IQR, interquartile range; NS, not significant.