Fig. 1.

(A) Schematic illustration of SARS-CoV-2 structure and its major structural proteins (B) the Schematic representation of the genomic organization of SARS-CoV-2. The distinct genomic locations, including ORFs, are represented. SARS-CoV-2 is comprised of four structural proteins, containing the E and M proteins responsible for the viral envelope, the N protein binding to the viral genome, and the spike protein capable of binding to the hACE2 receptor. Besides, translation of ORF 1a and ORF 1b to non-structural proteins (nsp) and accessory proteins, containing 3a, 6, 7a, 7b, 8, 9b, 9c, and 10 are indicated. Kb, kilobase pair, 3′-UTR 5′-UTR, untranslated regions at the 3′ and 5′ regions, respectively.