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. 2021 Feb 3;7:630880. doi: 10.3389/fmed.2020.630880

Table 3.

Major thickness measurements in OCTA between the RE and controls.

RE Control p
SVP + DVP in the macular area: ILM–RPE (μm)
   Whole image mean thickness (μm) 293.86 ± 17.12 296.08 ± 10.74 0.425
   Foveal thickness (ring diameter = 1 mm) (μm) 241.93 ± 23.70 244.95 ± 19.75 0.476
SVP in the macular area: ILM–IPL
   Whole image GCC mean thickness (μm) 97.86 ± 9.85 101.05 ± 5.88 *0.044
      Superior GCC thickness (μm) 95.74 ± 8.05 97.76 ± 5.71 0.143
      Inferior GCC thickness (μm) 94.23 ± 10.35 97.70 ± 5.20 *0.033
      FLV (%) 1.52 ± 2.64 0.81 ± 0.82 0.065
      GLV (%) 4.31 ± 5.36 1.96 ± 1.84 *0.003
   Foveal thickness (ring diameter = 1 mm) (μm) 48.87 ± 9.08 51.71 ± 8.60 0.101
   Parafoveal thickness (ring diameter = 3 mm) (μm) 103.29 ± 13.45 107.65 ± 6.81 *0.038
   Perifoveal thickness (ring diameter = 6 mm) (μm) 97.32 ± 10.65 100.93 ± 6.54 *0.038
DVP in the macular area: IPL–OPL
   Whole image mean thickness (μm) 48.87 ± 9.08 48.87 ± 9.08 0.185
RPE–BRM mean thickness (μm) 9.87 ± 2.21 11.22 ± 4.12 *0.049
Peripapillary RNFL (μm) 113.74 ± 17.31 117.40 ± 17.82 0.290
Sub-foveal choroidal thickness (μm) 262.22 ± 64.56 290.48 ± 69.52 *0.039

RE, radiation encephalopathy; SVP, superficial vascular plexus; DVP, deep vascular plexus; ILM, internal limiting membrane; RPE, retinal pigment epithelium; IPL, inner plexiform layer; GCC: ganglion cell complex, includes retinal nerve fiber layer, ganglion cell layer, and inner plexiform layer; FLV, focal loss volume, the sum of fractional deviation in the region where there is significant focal loss (pattern deviation more than 1.65 standard deviations below the normal average); GLV, global loss volume, the sum of fractional deviation in areas where fractional deviation is negative; OPL, outer plexiform layer; BRM, Bruch's membrane; RNFL, retinal nerve fiber layer. RNFL thickness, GCC thickness, FLV, and GLV were measurements in retinal ganglion cells assessment.

*

p < 0.05.