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. 2021 Feb 3;7:607323. doi: 10.3389/fmolb.2020.607323

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Copyright © 2021 Jernigan, Sankar, Jia, Faraggi and Kloczkowski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interfaces on HA that could likely be targeted in inhibitor design. (A) The interface conserved among Group 1 influenza A virus (in colors). (B) The interface conserved among all influenza A and B viruses. (C) The conserved patch on the surface of the central helical bundle at low-pH on HA.