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. 2021 Feb 16;10(4):e12064. doi: 10.1002/jev2.12064

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© 2021 The Authors. Journal of Extracellular Vesicles published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Sixteen out of the 48 significantly differentially expressed apical sEV molecules (defined miRNA/proteins) derived from inflammatory culture conditions compared to normal culture conditions associate with a cell death and survival/immunological disease pathway identified by the “Networks Function” of IPA. The red colour intensity indicates amount of up‐regulation within the network and the green colour intensity indicates amount of down‐regulation within the network. Molecules highlighted in bold within the data table are the 16 significantly differentially apical sEV miRNA/proteins.