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. 2021 Jan 28;163(3):843–852. doi: 10.1007/s00701-021-04708-3

Table 1.

Studies on augmented reality navigation in spine surgery

Authors Year Study type Study subjects Procedure Spine segments Interface type Patient registration/tracking type
Abe et al. [1] 2013 Cohort Phantom + patients Vertebroplasty Thoracolumbar HMD Preop CT and fluoroscopy/DRF
Elmi-Terander et al. [22] 2016 Controlled Cadaver Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Ma et al. [33] 2017 Cohort Phantom Pedicle screw Lumbar Projector Ultrasound/DRF
Elmi-Terander et al. [21] 2018 Cohort Cadaver Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Auloge et al. [2] 2019 RCT Patients Vertebroplasty Thoracolumbar Monitor Intraop CBCT/skin markers
Burström et al. [8] 2019 Cohort Cadaver (pig) Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Carl et al. [10] 2019 Cohort Patients Multiple All segments Microscope Intraop CT/DRF
Carl et al. [11] 2019 Cohort Patients Tumor Cervical, thoracic Microscope Intraop CT/DRF
Carl et al. [13] 2019 Cohort Patients Tumor All segments Microscope Intraop CT/DRF
Elmi-Terander et al. [20] 2019 Cohort Patients Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Gibby et al. [23] 2019 Cohort Phantom Pedicle screw Lumbar HMD (HoloLens) Manual adjustments/surface tracking
Liebmann et al. [30] 2019 Cohort Phantom Pedicle screw Lumbar HMD (HoloLens) Pointer/surface tracking
Liu et al. [31] 2019 Controlled Phantom Pedicle screw Lumbar HMD (HoloLens) Two groups: CT or manual/surface tracking
Molina et al. [36] 2019 Cohort Cadaver Pedicle screw Thoracolumbar HMD Intraop CT/DRF
Urakov et al. [42] 2019 Controlled Cadaver Pedicle screw Thoracolumbar HMD (HoloLens) Manual adjustments/surface tracking
Wanivenhaus et al. [45] 2019 Controlled Phantom Rod bending Lumbosacral HMD (HoloLens) Pointer/surface tracking
Wei et al. [46] 2019 RCT Patients Kyphoplasty Thoracolumbar HMD (HoloLens) Manual adjustments/surface tracking
Edstrom et al. [17] 2020 Cohort Patients Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Edstrom et al. [16] 2020 Cohort Patients Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Elmi-Terander et al. [19] 2020 Controlled Patients Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Muller et al. [37] 2020 Controlled Phantom/Cadaver Pedicle screw Lumbar HMD (HoloLens) Fluoroscopy/DRF
Edström et al. [18] 2020 Controlled Patients Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Peh et al. [38] 2020 Controlled Cadaver Pedicle screw Thoracolumbar Monitor Intraop CBCT/skin markers
Carl et al. [12] 2020 Cohort Patients Multiple All segments Microscope Intraop CT/DRF
Dennler et al. [14] 2020 Controlled Phantom Pedicle screw Lumbar HMD (HoloLens) Manual adjustments/surface tracking
Molina et al. [35] 2020 Cohort Cadaver Pedicle screw Thoracic and lumbosacral HMD Intraop CT/DRF
Siemionow et al. [40] 2020 Cohort Cadaver Pedicle screw Thoracolumbar Projector Intraop CT/DRF
von Atzigen et al. [44] 2020 Cohort Phantom Rod bending Lumbosacral HMD (HoloLens) Surface tracking

CT computed tomography, DRF dynamic reference frame, HMD head-mounted display, Preop preoperative, RCT randomized controlled trial