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. 2020 Dec 23;41(2):149–159. doi: 10.1007/s40261-020-00992-6
Viloxazine extended-release (ER) is under investigation as a non-stimulant treatment for attention-deficit/hyperactivity disorder and could be coadministered with other medications.
Viloxazine ER and methylphenidate were coadministered and the potential for pharmacokinetic interactions was evaluated.
Coadministration of viloxazine ER with methylphenidate did not impact the pharmacokinetics of either drug alone, and the combination appeared to be safe and well-tolerated.