Table 5.
Other biological functions of MI circulating biomarkers.
| Biomarkers | Application value | References | |
|---|---|---|---|
| S100 | S100A8 | Prevents myocardial ischemia and stabilize cardiac function after MI | (14) |
| S100B, S100A6, S100P |
*Associate with ischemic myocardial injury in ACS * Relate to myocardial infarct size |
(129) | |
| S100B |
*Down-regulate cardiac myocyte hypertrophy and apoptosis *Affect myocardial metabolism |
(74, 75) | |
| IL | sIL-1R2, IL-1, IL-6 | Associated with myocardial remodeling after MI | (64, 65, 100) |
| H-FABP |
*Involved in in-stent restenosis *Evaluate the degree of heart reperfusion after ischemic attack *Predict adverse cardiac events and provide risk evaluation |
(57, 58, 60, 92–94) | |
| IGF-1 |
*Affect atherosclerosis progression * Reduce adverse cardiac remodeling after cardiac I/R injury * Improve ventricular arrhythmia after myocardial infarction combined with HGF |
(102, 105, 106) | |
| microRNAs | microRNA-145 | Prognosticate cardiac function and the risk of developing HF | (40) |
| microRNA-1,microRNA-133, microRNA-208 | Diagnose sudden death due to early AMI sensitively | (138) | |
| microRNA-124 | Reduce cardiomyocyte apoptosis following MI | (41) | |
| microRNA-208b | Reduces post-infarction myocardial fibrosis in | (139) | |
| microRNA−93 | Inhibit cardiac remodeling and HF | (140) | |
| miR-24-3p | Exert cardioprotective effects in myocardial I/R injury | (141) | |
| VEGF | VEGF-A | Inversely correlated with LVEF after MI at 6-month follow-up | (45) |
| VEGF-C | Predict all-cause mortality independently | (113) |