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Medications used in the management of PSC and its complications
| Indication | Drugs |
|---|---|
| PSC | Ursodeoxycholic acid (UDCA): 15–20 mg/kg/day |
| Cholangitis | Antibiotics: in the pocket or prophylactic rotating ATBs |
| Pruritus | Bezafibrate, cholestyramine, rifampicin, naltrexone, sertraline |
| Autoimmune hepatitis | Predniso(lo)ne or budesonide, azathioprine |
| IBD | 5-ASA, corticosteroids, biologics |
PSC primary sclerosing cholangitis, IBD inflammatory bowel disease, 5-ASA 5-aminosalicylic acid, ATBs antibiotics
