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. 2021 Feb 16;11:3857. doi: 10.1038/s41598-021-83516-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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LX2 cells treated with hypoxia for 3 h and reoxygenation for different time with untreated LX2 cells as control. (A) Dynamics in the expression of CTGF mRNA in LX2 cells under hypoxia/reoxygenation (*P < 0.05). (B) Dynamic expressions of CTGF, YAP, p-YAP and p-SMAD2/3 in LX2 cells under hypoxia and reoxygenation culture conditions by WB and their quantifications (C–E) (*P < 0.05).