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. 2021 Feb 16;11:3857. doi: 10.1038/s41598-021-83516-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Expression of CTGF, YAP and TGF-β in non-steatotic liver and non-alcoholic steatotic liver under brain death. Expression of (A) CTGF, (B) TGF-β, and (C) YAP in the non-steatotic liver and non-alcoholic steatotic liver before and after brain dead in rats; n = 5 per group, scale bar = 20 μm, ×200 magnification (*P < 0.05 between the non-steatotic liver and non-alcoholic steatotic liver after brain death). (D) Expression of CTGF, TGF-βand YAP in human non-steatotic and non-alcoholic steatotic liver tissues (scale bar = 20 μm, ×200 magnification, n = 6). (E) Schematic of the proposed mechanism of CTGF regulation in the non-alcoholic steatotic liver after brain death.