Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 16;11:3873. doi: 10.1038/s41598-021-83209-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Short-term plasticity at PF-SC synapses. (A) EPSCs recorded from the SC during 50, 100 and 200 Hz parallel fiber stimulations (n = 6). Cells were voltage-clamped at − 70 mV and in the presence of gabazine. Each trace (black) is an average of 10 sweeps. Note that EPSC trains showed first facilitation and then depression. Simulations show that the model could faithfully reproduce the same behavior (blue traces; n = 4). (B) Comparison of peak amplitudes of experimental and simulated EPSCs during high-frequency parallel fiber stimulation. Amplitudes are normalized to the first EPSC in the train (correlation coefficient R² @ 50 Hz = 0.80; @ 100 Hz = 0.90; @ 200 Hz = 0.84). Data are reported as mean ± SEM.