. 2021 Feb 16;12:1050. doi: 10.1038/s41467-021-21283-4

Table 3.

Meta-analysis of full-sib IBD regression results for height, body mass index (BMI) and educational attainment (EA).

Trait	Study	N.pair	${\hat{r}}_{F S}^{a}$	s.e.	${\hat{c}}_{F S}^{2}$	s.e.	${\hat{h}}_{F S}^{2}$	s.e.
Height	This paper	19,954	0.53	0.01	0.23	0.06	0.60	0.12
	Young et al.¹²	64,847	0.41	0.01	0.07	0.05	0.68	0.10
	Hemani et al.²²	20,240	0.43	0.01	0.08	0.07	0.69	0.14
	Meta-analysis	105,041	0.44	<0.01	0.12	0.03	0.66	0.07
BMI	This paper	19,885	0.27	0.01	−0.13	0.08	0.81	0.17
	Young et al.¹²	56,461	0.27	0.01	0.08	0.06	0.39	0.12
	Hemani et al.²²	20,240	0.31	0.01	0.10	0.08	0.42	0.17
	Meta-analysis	96,586	0.28	<0.01	0.03	0.04	0.50	0.08
EA	This paper	19,736	0.29	0.01	0.22	0.08	0.14	0.16
	Young et al.¹²	32,542	0.36	0.01	0.16	0.07	0.40	0.15
	Meta-analysis	52,278	0.34	<0.01	0.19	0.06	0.28	0.11

Shown is the number of sib-pairs (N.pair) in each study, inferred full-sib correlation $({\hat{r}}_{F S})$ , common environmental effect ( ${\hat{c}}_{F S}^{2}$ ) and heritability ( ${\hat{h}}_{F S}^{2}$ ) with standard errors (s.e.).

^ain each study, we calculated the full-sib correlation from the given estimates of common environmental and genetic effects from full-sib regression as ${\hat{c}}_{F S}^{2} + \frac{1}{2} {\hat{h}}_{F S}^{2}$ . Standard errors were estimated using the approximation $\sqrt{(1 - {\hat{r}}_{F S}^{2}) / N}$ , where N is the number of pairs.