Table 3.

Loneliness, chronic pain, and C-reactive protein.

	Grouping	%	Adjusted OR (95% CI)	P
Loneliness and CRP as predictors of future chronic pain	Low lonely/low CRP	49.2%	1 (ref)*
	Low lonely/high CRP	21.9%	1.27 (1.03-1.58)	0.028
	High lonely/low CRP	19.0%	1.36 (1.07-1.71)	0.011
	High lonely/high CRP	9.8%	1.50 (1.13-2.00)	0.006
Chronic pain and CRP as predictors of future loneliness	No pain/low CRP	55.6%	1 (ref)†
	No pain/high CRP	21.3%	0.93 (0.75-1.15)	0.43
	Pain/low CRP	12.7%	1.34 (1.04-1.73)	0.023
	Pain/high CRP	10.5%	1.35 (1.02-1.78)	0.036

CRP, C-reactive protein.

^*Adjusted for age, sex, baseline chronic pain, ethnicity, education, wealth, marital status, physical activity, and depressive symptoms.

^†Adjusted for age, sex, baseline loneliness, ethnicity, education, wealth, marital status, physical activity, and depressive symptoms.