Why carry out this study?

Limited data exist on the impact of thyroid eye disease (TED) on quality of life (QOL) in US patients, particularly physician-perceived QOL which directly influences TED severity classification and treatment decisions.

This large-scale study of a rare condition sought to examine QOL in US patients with moderate-to-severe TED and to determine influencing factors.

What was learned from the study?

QOL is heavily impacted by both moderate and severe TED in US patients.

Higher disease activity and more severe disease were associated with a greater QOL impact, more specifically, orbital pain, visual disturbances (including diplopia), and orbito-facial structural changes.