TABLE 6.
Relationships between frontal NAA, parietal Cho, cortical white matter volume, and hippocampal volume to cognitive performance.
| ROI | β | SE | Multiple R2 | Adjusted R2 | F | P |
| MoCA | 0.10 | 0.09 | F(1, 77) = 8.57 | 4.50 × 10–3 | ||
| Hippocampus | 0.84 | 0.29 | 4.50 × 10–3 | |||
| CVLT discrimination | 0.17 | 0.14 | F(3, 75) = 5.10 | 2.89 × 10–3 | ||
| Cortical white matter | −1.17 | 0.46 | 0.01 | |||
| Hippocampus | 1.16 | 0.41 | 5.54 × 10–3 | |||
| Age | −0.55 | 0.26 | 0.04 | |||
| Trails A | NS | |||||
| Trails B | NS | |||||
| Crystallized – fluid discrepancy | 0.12 | 0.10 | F(2, 76) = 5.20 | 7.66 × 10–3 | ||
| Parietal Cho | −3.69 | 1.74 | 0.04 | |||
| Hippocampus | −5.25 | 1.82 | 5.05 × 10–3 |
Variables reported were selected by the adaptive LASSO models as important predictors of regional volumes. p-values are generated via post-inferential linear regression. Adjusted R2 values are for the whole model fit.