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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Anesth Analg. 2021 Mar 1;132(3):878–889. doi: 10.1213/ANE.0000000000005268

Figure 2. Clonidine attenuates sevoflurane-induced Tau phosphorylation and sevoflurane-induced reduction in PSD-95 in the hippocampi of young mice.

Figure 2.

A. Tau-PS202/Tau-PT205 in the hippocampi of the young mice after clonidine and sevoflurane treatments. B. Quantification of the western blot in A. There were no significant changes of total Tau amounts in the different conditions (C and D). E. Quantification of the western blots in A and C presented as the ratio of Tau-PS202/Tau-PT205 to total Tau. F. PSD-95 in the hippocampi of young mice compared to control at P37 under sevoflurane and clonidine treatment. G. Quantification of the western blot in F. There were no significant differences in the β-Actin amounts among treatments. P, postnatal; PSD, postsynaptic density; Tau-PS202, phosphorylated at serine-202; Tau-PT205, Tau phosphorylated at threonine 205. A one-way ANOVA with Bonferroni’s multiple comparison test was used to analyze the data. N = 6 in each group.