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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Anesth Analg. 2021 Mar 1;132(3):878–889. doi: 10.1213/ANE.0000000000005268

Figure 3. Yohimbine inhibits the protective effects of dexmedetomidine on attenuating sevoflurane-induced Tau phosphorylation and reduction in PSD-95 in the hippocampi of young mice.

Figure 3.

A. Tau-PS202/Tau-PT205 in the hippocampi of young mice under various treatment conditions. B. Quantification of the western blot in A. There were no significant changes in total Tau among the different conditions (C and D). E. Quantification of the western blots in A and C presented as the ratio of Tau-PS202/Tau-PT205 to total Tau in the hippocampi of young mice. F. PSD-95 in the hippocampi of young mice under various treatment conditions. G. Quantification of the western blot in F. There were no significant differences in the β-Actin amounts in the hippocampi of the young mice among the different conditions. P, postnatal; PSD, postsynaptic density, Tau-PS202, Tau phosphorylated at serine-202; Tau-PT205, Tau phosphorylated at threonine 205. A one-way ANOVA with Bonferroni’s multiple comparison test was used to analyze the data. N = 6 in each group.