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. Author manuscript; available in PMC: 2021 Aug 15.
Published in final edited form as: Clin Cancer Res. 2020 Nov 13;27(4):1082–1093. doi: 10.1158/1078-0432.CCR-20-2667

Figure 5.

Figure 5

Prognostic significance of aneuploidy in patient samples. a) Exemplary segmentation plots intersected with HapLOHseq calls (lavender background) showing samples classifying into aneuploidy low (<=7 chromosomal arm events) and aneuploidy high (>=8). b) Kaplan Meier curves comparing progression free survival (PFS) of patients with low vs. high aneuploidy levels (p=0.009). c) Kaplan Meier curves comparing overall survival (OS) of patients with low vs. high aneuploidy levels (p=0.06). d) Kaplan Meier curves comparing progression free survival (PFS) of patients with low vs. high aneuploidy levels for patients with localized tumors only (p=0.02). e) Kaplan Meier curves comparing overall survival (OS) of patients with low vs. high aneuploidy levels in localized patients only (p=0.04). *For this and subsequent figures HapLOHseq calls shown pass a threshold of posterior probability of AI >0.85.