Table 5.

Controller Medication Treatment Algorithm (Applied only to subjects currently taking controller medications)

Symptom Level (from Table 4)	Treatment Algorithm for Participants with Acceptable Adherence (≥50% of prescribed controller doses taken)	Treatment Algorithm for Participants with Unacceptable Adherence (< 50% of prescribed controller doses taken)
	If participant has been on their current Step (1–6) for <6 weeks – no change in treatment	If participant has been on their current Step (1–6) for <6 weeks – no change in treatment
Well Controlled (Symptom level 1)	If participant has been on their current Step (1–6) for ≥6 weeks – decrease treatment by one step unless the participant has taken prednisolone for respiratory symptoms within the previous 28 days.	If participant has been on their current Step (1–6) for ≥6 weeks – decrease treatment by one step unless the participant has taken prednisolone for respiratory symptoms within the previous 28 days.
	Assess acute symptoms for initiation of prednisone	Assess acute symptoms for initiation of prednisone
Not Well Controlled (Symptom level 2)	If currently on Steps 1–5, increase controller regimen by 1 Step or,	Continue same controller regimen or place on Step 2 therapy, whichever is higher
	If currently on Step 6, continue Step 6
	Assess acute symptoms for initiation of prednisone	Assess acute symptoms for initiation of prednisone