Table 3.
rhACE2 Km, Vmax, Kcat and Kcat/Km values for the metabolism of Ang II and Ang V.
Substrate | Km (μM) | Vmax (nmol /30 min | Kcat (sec−1) | Kcat/Km (μm−1 sec−1) |
---|---|---|---|---|
Ang II | 8.41 ± 2.69 | 2.21 ± 0.18 | 8.42 ± 1.61 | 1.13 ± 0.25 |
Ang V | 8.23 ± 3.23 | 7.13 ± 0.49* | 31.7 ± 2.6* | 6.22 ± 3.24 |
p < 0.05 greater than Ang II; Values are mean ± SEM, n= 3