Table 2.
Summary of possible mechanisms connecting long sleep with cardiovascular risk factors.
Pathway to Cardiovascular Disease | Correlates to long sleep |
---|---|
Metabolic | -low HDL [36, 37] -hyperglycemia [27] -hypertriglyceridemia [27] -insulin dysregulation and resistance [33] |
Inflammation | -high CRP [37, 39] -high IL-6 [37, 39] |
Behavioral/Lifestyle | -depression [43, 44] -low socio-economic status [43, 44] -unemployment [43, 44] -insufficient physical activity [43, 44] -increased alcohol consumption [37] -smoking [37] |