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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Sleep Med. 2020 Dec 14;78:135–140. doi: 10.1016/j.sleep.2020.12.011

Table 2.

Summary of possible mechanisms connecting long sleep with cardiovascular risk factors.

Pathway to Cardiovascular Disease Correlates to long sleep
Metabolic -low HDL [36, 37]
-hyperglycemia [27]
-hypertriglyceridemia [27]
-insulin dysregulation and resistance [33]
Inflammation -high CRP [37, 39]
-high IL-6 [37, 39]
Behavioral/Lifestyle -depression [43, 44]
-low socio-economic status [43, 44]
-unemployment [43, 44]
-insufficient physical activity [43, 44]
-increased alcohol consumption [37]
-smoking [37]
*

[31][36][43] define long sleep as ≥8 h

**

[27][33][34][42] define long sleep as ≥9 h