Table 2.
Laboratory tests by TB statusa
| N | All | No TB b | TB | Contacts | TB vs no TB b p value c | TB vs Contacts p value c | |
|---|---|---|---|---|---|---|---|
| Lipids (mg/dL) | 60 | ||||||
| Total Cholesterol (200) | 60 | 174.5 (42) | 174.5 (42) | 132.5 (26.5) | 171 (40) | <0.001 | <0.001 |
| HDL (40 M, 50 F) | 62 | 43 (12) | 43 (12) | 35 (13.5) | 43 (13) | 0.001 | 0.002 |
| LDL (100) | 60 | 109.5 (50.6) | 109.5 (50.6) | 75.2 (26.3) | 97.5 (47.1) | <0.001 | 0.001 |
| Triglycerides (150) | 63 | 111 (75) | 111 (75) | 89.5 (34.5) | 114 (105) | 0.017 | 0.036 |
| Complete blood counts (x10e3/μl) Platelets (146–388) | 46 | 253 (81.5) | 253 (81.5) | 441 (238) | 252 (82) | <0.001 | <0.001 |
| White blood cells (4.8–10.9) | 46 | 6.7 (2.4) | 6.7 (2.4) | 8.8 (2.2) | 6.5 (2.7) | 0.007 | 0.009 |
| Neutrophils (2.3–7.7) | 46 | 3.9 (1.6) | 3.9 (1.6) | 5.7 (3.1) | 3.7 (1.6) | 0.001 | 0.001 |
| Lymphocytes (0.8–3.3) | 46 | 1.8 (1) | 1.8 (1) | 1.2 (0.9) | 1.8 (1.1) | 0.008 | 0.018 |
| Monocytes (0.2–1.0) | 46 | 0.5 (0.2) | 0.5 (0.2) | 0.6 (0.3) | 0.5 (0.2) | 0.009 | 0.015 |
| Monocyte:lymphocyte ratio | 46 | 0.2 (0.2) | 0.2 (0.2) | 0.4 (0.4) | 0.2 (0.1) | <0.001 | <0.001 |
| Neutrophil:lymphocyte ratio | 46 | 2.2 (1.3) | 2.2 (1.3) | 5 (5.1) | 1.8 (1.3) | <0.001 | <0.001 |
a
Data expressed as median (interquartile range);
b
No TB = Contacts + healthy;
c
Non-parametric measures used to compare median values between study groups for variables with two levels (Wilcoxon rank sum test) or more than two levels (Kruskall-Wallis), with P values in bold highlight significant and borderline significant results; HDL = High density cholesterol; LDL= Low density cholesterol; Note: Healthy controls alone are not shown given no significant differences with TB contacts; Normal cut-offs values or ranges are indicated in parenthesis, in mg/dL units for lipids and x10e3/μl for complete blood counts; M=males; F=females;