Table 1:
Baseline Characteristics by Tertile of Genetic Risk
| Participants (n) | 9,888 | 9,887 | 9,888 | |
|---|---|---|---|---|
| FOURIER (%) | 42 | 44 | 45 | |
| PEGASUS (%) | 37 | 36 | 35 | |
| SAVOR (%) | 21 | 20 | 20 | |
| Demographics | ||||
| Age (yr) (+/−SD) | 64.5 ± 8.7 | 64.2 ± 8.6 | 64.0 ± 8.5 | <0.001 |
| Male Sex (%) | 7,365 (74) | 7,442 (75) | 7,319 (74) | 0.12 |
| BMI (+/−SD) | 29.9 ± 5.1 | 30.0 ± 5.2 | 29.9 ± 5.1 | 0.33 |
| Medical History (%) | ||||
| Myocardial Infarction | 7,896 (80) | 7,954 (80) | 7,905 (80) | 0.53 |
| Stroke | 872 (9) | 906 (9) | 942 (10) | 0.23 |
| Peripheral Artery Disease | 1,037 (11) | 979 (10) | 1,093 (11) | 0.03 |
| Hypertension | 7,833 (79) | 7,913 (80) | 7,892 (80) | 0.33 |
| Heart Failure | 1,900 (19) | 1,982 (20) | 2,043 (21) | 0.04 |
| Diabetes | 4,487 (45) | 4,536 (46) | 4,463 (45) | 0.56 |
| Current Smoker | 2,164 (22) | 2,150 (22) | 2,302 (23) | 0.16 |
yr = years; SD = standard deviation; BMI = body mass index