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. 2021 Feb 16;11:3876. doi: 10.1038/s41598-021-83496-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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CD44 expression on leukocytes isolated from spleen of mice with or without LPS treatment. Representative forward and side scatter analysis plots show an increase of cells in R2 after mice were treated with LPS (top). Flow cytometry histograms using FITC-anti-CD44 show that LPS stimulates a substantial increase of CD44 expression on cells in R2 but not R1 (bottom).