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. 2021 Feb 16;11:3908. doi: 10.1038/s41598-021-82343-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene expression difference and network for the 15 lipid metabolism- or autophagy-associated genes selected from the pink module. (A) The FPKM differences (normalized by J2) between DJ3-lab and the other PWN stages. Genes in the black box are associated with autophagy, while those in the khaki box are associated with lipid metabolism. (B) Gene network for the 15 candidate genes. The size of the dots represents GS (from 0.9361 to 0.9984). Prefuse Force Directed Layout was applied based on the weight value between two genes. The color of the dots represents log₂fold (from 2.3238 to 6.7868) for the FPKM of DJ3-lab vs. the average FPKM of the other samples. The color of the lines represents the weight value between the two genes (from 0.3770 to 0.4864). The label of dots is listed based on IC (from 108.1303 to 159.5326).