Figure 1.

Brain magnetic resonance imaging results of the two patients in the present study. Brain magnetic resonance imaging of patient one in our study at 1 month old revealed cerebral atrophy and partial encephalomalacia, a diffuse abnormal signal in the cerebral white matter, with a low signal in T1WI (A) and a high signal in T2WI (B), and high signals in the bilateral occipital and temporal lobes, basal ganglia and thalamus (C). An MRI of patient two at 3 months old indicated polycystic encephalomalacia and diffuse cerebral atrophy, with diffuse abnormal signals in the brain, low signals on T1WI and high signals on T2WI and DWI (D–F), and a high signal in the cerebral peduncle (G–I).