Table 2.

GO and KEGG pathway analyses of EGRs.

	Term description	False discovery rate
GO_BP	Transcription by RNA polymerase II	3.53E-08
	Positive regulation of macromolecule biosynthetic process	4.77E-08
	Positive regulation of transcription by RNA polymerase II	4.77E-08
	Positive regulation of macromolecule metabolic process	5.17E-08
	Positive regulation of nitrogen compound metabolic process	2.02E-07
GO_CC	Transcription factor AP-1 complex	0.0031
	Nucleus	0.0043
	Nuclear chromosome	0.0123
	RNA polymerase II transcription factor complex	0.0166
	Transcription regulator complex	0.0166
GO_MF	DNA-binding transcription activator activity, RNA polymerase II-specific	2.65E-12
	Sequence-specific DNA binding	2.31E-09
	DNA-binding transcription factor activity, RNA polymerase II-specific	3.92E-07
	Transcription regulator activity	4.83E-07
	RNA polymerase II regulatory region sequence-specific DNA binding	9.13E-07
KEGG	Th1 and Th2 cell differentiation	2.91E-06
	Th17 cell differentiation	3.40E-06
	T cell receptor signaling pathway	3.40E-06
	B cell receptor signaling pathway	2.25E-05
	IL-17 signaling pathway	0.0249
	Natural killer cell-mediated cytotoxicity	0.039

FDR < 0.05 was considered statistically significant. GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; BP, biological processes; CC, cellular components; MF, molecular function; FDR, false discovery rate.