Table 1.
Metabolic alteration in various virus infection.
| Virus | Nucleic acid | Cells used | Metabolism targeted | Action | Reference |
|---|---|---|---|---|---|
| Adeno virus | DNA | Non-tumorigenic epithelial cell line (MCF10A cells) | Glycolysis | upregulated | (9) |
| HCMV | MRC-5 (human fetal lung) fibroblasts | (10) | |||
| EBV | Nasopharyngeal carcinoma cells | (11) | |||
| KSHV | Human B-cell non-Hodgkin lymphomas and primary effusion lymphoma | (12) | |||
| HCV | RNA | U-2 OS human osteosarcoma-derived tetracycline-regulated cell line | (13) | ||
| HIV | Primary CD4+ T cells from donor |
(14) | |||
| DENV | Primary dermal fibroblast normal; human, neonatal cells | (15) | |||
| IAV | Madin-Darby canine kidney cells | (16) | |||
| HCMV | DNA | Human foreskin fibroblasts | Glutaminolysis | (17) | |
| KSHV | Tert-immortalized microvascular endothelial cells | (18) | |||
| Vaccinia virus | Primary human foreskin fibroblasts | (19) | |||
| HCMV | DNA | MRC-5 fibroblasts | Fatty acid synthesis | (10) | |
| KSHV | Human B-cell non-Hodgkin lymphomas and primary effusion lymphoma | (12) | |||
| HCV | RNA | Huh-7 cell | (20, 21) | ||
| DENV | Human embryonic lung cells | (22) |
EBV, Epstein-Barr virus; IAV, influenza A virus; KSHV, Kaposi’s sarcoma-associated herpesvirus; DENV, dengue virus; HCV, hepatitis C virus; HCMV, human cytomegalovirus.