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Determination of person-years of exposure. (A) Total person-years of each patient were divided into three categories: current use of PPIs, recent use of PPIs and past use of PPIs. (B) The duration of concomitant use of NSAIDs or antibiotics with PPIs was defined as the amount of time when the current use of PPIs overlapped with the current use of NSAIDs or antibiotics. AKI, acute kidney injury; NSAIDs, non-steroidalanti-inflammatory drugs; PPIs, proton pump inhibitors.
